A prospective study of cognitive function and onset of dementia in cognitively healthy elders
EH Rubin, M Storandt, JP Miller… - Archives of …, 1998 - jamanetwork.com
Objective To examine the earliest cognitive changes associated with the onset of dementia
as well as changes associated with normal aging. Design Longitudinal evaluation of
participants with annual clinical and psychometric examinations for up to 15½ years. Setting
and Participants Elderly volunteers (n= 82) enrolled with a Clinical Dementia Rating of 0
(cognitively intact) in longitudinal studies. Interventions None. Main Outcome Measures
Clinical Dementia Rating and results of a 1½-hour psychometric battery. Results As …
as well as changes associated with normal aging. Design Longitudinal evaluation of
participants with annual clinical and psychometric examinations for up to 15½ years. Setting
and Participants Elderly volunteers (n= 82) enrolled with a Clinical Dementia Rating of 0
(cognitively intact) in longitudinal studies. Interventions None. Main Outcome Measures
Clinical Dementia Rating and results of a 1½-hour psychometric battery. Results As …
