Automated software package for icosahedral virus reconstruction

JA Lawton, BVV Prasad - Journal of structural biology, 1996 - Elsevier
The three-dimensional reconstruction of icosahedral viruses from electron micrograph
images has become an important tool for understanding virus structure, function, and
pathogenesis. We have developed an integrated suite of software programs to automate
most of the operations involved in producing these reconstructions from EM images. Our
package combines the analytical capabilities of preexisting algorithms together with
approaches we have developed to produce an interactive working environment which …