Mediation of ARDS by leukocytes: clinical evidence and implications for therapy
JE Rinaldo - Chest, 1986 - journal.chestnet.org
The mortality rate for AROS remains extremely high. 1 It is now widely believed that
elucidation of the pathophysiology ofcell injury and aberrant repair in ARDS will be
necessary to substantially influence survival rates by identifying appropriate pharmacologic
therapy. In recent years, attention has been directed towards blood leukocytes as major
mediators of acute lung injury in ARDS. The role of blood leukocytes as mediators of
pathophysiology is of theoretical interest but more importantly suggests potential therapeutic …
elucidation of the pathophysiology ofcell injury and aberrant repair in ARDS will be
necessary to substantially influence survival rates by identifying appropriate pharmacologic
therapy. In recent years, attention has been directed towards blood leukocytes as major
mediators of acute lung injury in ARDS. The role of blood leukocytes as mediators of
pathophysiology is of theoretical interest but more importantly suggests potential therapeutic …
