The effects of vasoactive intestinal peptide on monocrotaline induced pulmonary hypertensive rabbits following cardiopulmonary bypass: a comparative study with …
S Gunaydin, Y Imai, Y Takanashi, K Seo, I Hagino… - Cardiovascular …, 2002 - Elsevier
Background: Vasoactive intestinal peptide (VIP) has regulatory effects on myocardial and
vasomotor functions usually demonstrated by in vitro or isolated heart studies. We studied in
vivo effects in monocrotaline induced pulmonary hypertensive rabbits immediately after
cardiopulmonary bypass (CPB) and tested them versus calcium channel and beta-blockers.
Methods: The study consisted of six groups (N= 30; five rabbits/group):(1) Control with no
pretreatment, monocrotaline injected groups:(solutions were perfused following termination …
vasomotor functions usually demonstrated by in vitro or isolated heart studies. We studied in
vivo effects in monocrotaline induced pulmonary hypertensive rabbits immediately after
cardiopulmonary bypass (CPB) and tested them versus calcium channel and beta-blockers.
Methods: The study consisted of six groups (N= 30; five rabbits/group):(1) Control with no
pretreatment, monocrotaline injected groups:(solutions were perfused following termination …
