Effects of vaccination against different T cell receptors on maintenance of immune function during murine retrovirus infection

B Liang, JJ Marchalonis, Z Zhang, RR Watson - Cellular immunology, 1996 - Elsevier
Murine retrovirus infection causes an aberrant stimulation of several subsets of T helper 2
cells identified by their T cell receptors (TCR). C57BL/6 mice were treated with synthetic
peptides based upon different human TCR Vβ CDR1 sequences following experimental
infection with the murine retrovirus. Previous studies established that retrovirally infected
mice produced autoantibodies to certain of these peptides, and their administration after
infection diminished many of the cytokine abnormalities induced by the virus. This study …