Optical biosensors are emerging as important tools for characterizing the interactions of
biological macromolecules. Biosensors can provide qualitative information on
macromolecular assembly processes under a variety of conditions. Quantitative information,
in the form of affinity constants for complex formation, can be obtained in a manner similar to
conventional solid-phase assays. The major advantage of biosensors over other interaction
technologies is that the formation and breakdown of complexes can be monitored in real …