[HTML][HTML] A transmembrane tight junction protein selectively expressed on endothelial cells and platelets
I Nasdala, K Wolburg-Buchholz, H Wolburg… - Journal of Biological …, 2002 - ASBMB
Searching for cell surface proteins expressed at interendothelial cell contacts, we have
raised monoclonal antibodies against intact mouse endothelial cells. We obtained two
monoclonal antibodies, 1G8 and 4C10, that stain endothelial cell contacts and recognize a
protein of 55 kDa. Purification and identification by mass spectrometry of this protein
revealed that it contains two extracellular Ig domains, reminiscent of the JAM family, but a
much longer 120-amino acid cytoplasmic domain. The antigen is exclusively expressed on …
raised monoclonal antibodies against intact mouse endothelial cells. We obtained two
monoclonal antibodies, 1G8 and 4C10, that stain endothelial cell contacts and recognize a
protein of 55 kDa. Purification and identification by mass spectrometry of this protein
revealed that it contains two extracellular Ig domains, reminiscent of the JAM family, but a
much longer 120-amino acid cytoplasmic domain. The antigen is exclusively expressed on …
