Human herpesvirus 8 glycoprotein K8. 1: expression, post-translational modification and localization analyzed by monoclonal antibody
L Wu, R Renne, D Ganem, B Forghani - Journal of clinical virology, 2000 - Elsevier
Background: The genome of human herpesvirus 8 (HHV-8) contains at least 84 open
reading frames, including the highly immunogenic K8. 1. Other studies have determined that
K8. 1 gene generates at least two spliced transcripts in the HHV-8 infected BCBL-1 cells,
termed as glycoprotein (gp) K8. 1A and gpK8. 1B. Objective: To analyze the expression, post-
translational modification and localization of HHV-8 gpK8. 1 by monoclonal antibody (mAb).
Study design: Mabs to HHV-8 produced by conventional hybridization and several clones …
reading frames, including the highly immunogenic K8. 1. Other studies have determined that
K8. 1 gene generates at least two spliced transcripts in the HHV-8 infected BCBL-1 cells,
termed as glycoprotein (gp) K8. 1A and gpK8. 1B. Objective: To analyze the expression, post-
translational modification and localization of HHV-8 gpK8. 1 by monoclonal antibody (mAb).
Study design: Mabs to HHV-8 produced by conventional hybridization and several clones …
