All patients with Werner's syndrome are insulin resistant, but only those who also have impaired insulin secretion develop overt diabetes.

K Yamada, H Ikegami, H Yoneda, T Miki… - Diabetes …, 1999 - search.ebscohost.com
K Yamada, H Ikegami, H Yoneda, T Miki, T Ogihara
Diabetes Care, 1999search.ebscohost.com
All Patients Wi th We rn er ’s Syndro me A re Insulin Resistant, But Only Those Who Also Have
Impaire d Insulin Secre tio Page 1 2094 DIABETES CARE, VOLUME 22, NUMBER 12,
DECEMBER 1999 Letters WW, Gay EC, Hamman RF: Birth size and risk of insulin-dependent
diabetes mellitus (IDDM). Diabetes Res Clin Pract 2 4 : 1 5 3 – 159, 1994 4 . Bock T, Pedersen
CR, Volund A, Pallesen CS, Buschard K: Perinatal determ inants among children who later
develop IDDM. Diabetes Care 17:1154–1157, 1994 5 . Blom L, Persson LA, Dahlquist G: A high …
Abstract
Focuses on a study which examined the relationship between glucose tolerance and insulin secretory capacity in syndromes with extreme insulin resistance. Information on Werner's syndrome; Reason for the heterogeneity among patients; Implications of the results.
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