Transfusion-related acute lung injury: report of a clinical look-back investigation
PM Kopko, CS Marshall, MR MacKenzie, PV Holland… - Jama, 2002 - jamanetwork.com
ContextTransfusion-related acute lung injury (TRALI) is a syndrome that includes dyspnea,
hypotension, bilateral pulmonary edema, and fever. TRALI is the third leading cause of
transfusion-related mortality, but it is probably underdiagnosed and underreported.
ObjectiveTo determine if blood products from a frequent plasma donor, whose blood product
was implicated in a fatal case of TRALI, caused symptoms of TRALI in other recipients of her
plasma. Design, Setting, and ParticipantsRetrospective chart review (conducted from …
hypotension, bilateral pulmonary edema, and fever. TRALI is the third leading cause of
transfusion-related mortality, but it is probably underdiagnosed and underreported.
ObjectiveTo determine if blood products from a frequent plasma donor, whose blood product
was implicated in a fatal case of TRALI, caused symptoms of TRALI in other recipients of her
plasma. Design, Setting, and ParticipantsRetrospective chart review (conducted from …
