Synergically increased expression of CD36, CLA-1 and CD68, but not of SR-A and LOX-1, with the progression to foam cells from macrophages

K Tsukamoto, M Kinoshita, K Kojima… - … of atherosclerosis and …, 2002 - jstage.jst.go.jp
K Tsukamoto, M Kinoshita, K Kojima, Y Mikuni, M Kudo, M Mori, M Fujita, E Horie…
Journal of atherosclerosis and thrombosis, 2002jstage.jst.go.jp
Macrophages in the arterial wall play a crucial and central role in the progression of
atherosclerosis. The first step of atherosclerosis is the recruitment of monocytes from the
circulation into the arterial wall, wherein they transform to macrophages and foam cells.
During this transformation, macrophages take up negatively charged macromolecules
including oxidized LDL
Macrophages in the arterial wall play a crucial and central role in the progression of atherosclerosis. The first step of atherosclerosis is the recruitment of monocytes from the circulation into the arterial wall, wherein they transform to macrophages and foam cells. During this transformation, macrophages take up negatively charged macromolecules including oxidized LDL
jstage.jst.go.jp