The ryanodine receptor in cardiac physiology and disease
A Kushnir, AR Marks - Advances in pharmacology, 2010 - Elsevier
Abstract According to the American Heart Association it is estimated that the United States
will spend close to $39 billion in 2010 to treat over five million Americans suffering from
heart failure. Patients with heart failure suffer from dyspnea and decreased exercised
tolerance and are at increased risk for fatal ventricular arrhythmias. Food and Drug
Administration-approved pharmacologic therapies for heart failure include diuretics,
inhibitors of the renin–angiotensin system, and β-adrenergic receptor antagonists. Over the …
will spend close to $39 billion in 2010 to treat over five million Americans suffering from
heart failure. Patients with heart failure suffer from dyspnea and decreased exercised
tolerance and are at increased risk for fatal ventricular arrhythmias. Food and Drug
Administration-approved pharmacologic therapies for heart failure include diuretics,
inhibitors of the renin–angiotensin system, and β-adrenergic receptor antagonists. Over the …