Myeloid differentiation (MyD) primary response genes in hematopoiesis

DA Liebermann, B Hoffman - Blood Cells, Molecules, and Diseases, 2003 - Elsevier
Myeloid differentiation (MyD) primary response and growth arrest DNA-damage (Gadd)
genes comprise a set of overlapping genes, including known (IRF-1, EGR-1, Jun) and novel
(MyD88, Gadd45a MyD118/Gadd45b, GADD45g, MyD116/Gadd34) genes, that have been
cloned by virtue of being coordinately induced upon the onset of terminal myeloid
differentiation. This review delineates the role MyD genes were found to play in blood cell
development, where they function as positive regulators of terminal differentiation, lineage …