Design and synthesis of a highly selective EP4-receptor agonist. Part 1: 3, 7-dithiaPG derivatives with high selectivity
T Maruyama, M Asada, T Shiraishi, A Ishida… - Bioorganic & medicinal …, 2001 - Elsevier
T Maruyama, M Asada, T Shiraishi, A Ishida, H Egashira, H Yoshida, T Maruyama…
Bioorganic & medicinal chemistry letters, 2001•ElsevierDesign and synthesis of a highly selective EP4-receptor agonist. part 1: 3,7-dithiaPG
derivatives with high selectivity - ScienceDirect Skip to main contentSkip to article Elsevier
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ScienceDirect Elsevier Bioorganic & Medicinal Chemistry Letters Volume 11, Issue 15, 6
August 2001, Pages 2029-2031 Bioorganic & Medicinal Chemistry Letters Design and
synthesis of a highly selective EP4-receptor agonist. part 1: 3,7-dithiaPG derivatives with …
derivatives with high selectivity - ScienceDirect Skip to main contentSkip to article Elsevier
logo Journals & Books Search RegisterSign in View PDF Download full issue Search
ScienceDirect Elsevier Bioorganic & Medicinal Chemistry Letters Volume 11, Issue 15, 6
August 2001, Pages 2029-2031 Bioorganic & Medicinal Chemistry Letters Design and
synthesis of a highly selective EP4-receptor agonist. part 1: 3,7-dithiaPG derivatives with …
A series of 3,7-dithiaPGE1 analogues 3, 4, 11, 16 and 19 were identified as highly selective EP4-receptor agonists starting from the chemical modification of 7-thiaPGE1 analogue 1. EP4-receptor selectivity and agonist activity were maximized in 3 and 4.
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