[PDF][PDF] Augmented inflammatory cytokines in primary dengue infection progressing to shock
N Iyngkaran, M Yadav, M Sinniah - Singapore medical journal, 1995 - smj.org.sg
The report provides unequivocal evidence for the development of DSS in primary dengue
infection caused by virus serotype 4. The close relationship between sequential changes in
the levels of tumour necrosis factor (TNF), Interleukin I and 6 (IL-1 and IL-6) in the serum, to
the clinical progression of the disease from DF to DHF/DSS and then to full recovery
implicates a pathogenetic role for the inflammatory cytokines. The child also manifested
clinical features consistent with Reye's syndrome and this suggests a common pathogenetic …
infection caused by virus serotype 4. The close relationship between sequential changes in
the levels of tumour necrosis factor (TNF), Interleukin I and 6 (IL-1 and IL-6) in the serum, to
the clinical progression of the disease from DF to DHF/DSS and then to full recovery
implicates a pathogenetic role for the inflammatory cytokines. The child also manifested
clinical features consistent with Reye's syndrome and this suggests a common pathogenetic …
