Initial fetal platelet counts predict the response to intravenous gammaglobulin therapy in fetuses that are affected by PLA1 incompatibility

S Gaddipati, RL Berkowitz, AA Lembet… - American journal of …, 2001 - Elsevier
Objective: Fetal alloimmune thrombocytopenia is the result of maternal fetal platelet antigen
incompatibility; intracranial hemorrhage is its most serious complication. Our previous
studies have demonstrated an inability to accurately predict fetal platelet counts in this
disorder. The goal of the present investigation was to identify factors that would predict the
response of the fetal platelet count to therapy so that use of fetal blood sampling could be
minimized. Study Design: Patients who were eligible for the study were all those who (1) had …