Parthenogenetic stem cells in nonhuman primates
JB Cibelli, KA Grant, KB Chapman, K Cunniff, T Worst… - Science, 2002 - science.org
Science, 2002•science.org
Parthenogenesis is the process by which an egg can develop into an embryo in the absence
of sperm. This process has been characterized to some extent in nonhuman primates (1, 2);
however, to date, no primate parthenogenetic embryonic stem (ES) cell lines have been
derived. Although attempts to obtain full-term mouse and bovine parthenogenetic individuals
have failed (3–5), chimeras of parthenogenetic cells with biparentally derived embryonic
tissues have generated apparently normal offspring
of sperm. This process has been characterized to some extent in nonhuman primates (1, 2);
however, to date, no primate parthenogenetic embryonic stem (ES) cell lines have been
derived. Although attempts to obtain full-term mouse and bovine parthenogenetic individuals
have failed (3–5), chimeras of parthenogenetic cells with biparentally derived embryonic
tissues have generated apparently normal offspring
Parthenogenesis is the process by which an egg can develop into an embryo in the absence of sperm. This process has been characterized to some extent in nonhuman primates (1, 2); however, to date, no primate parthenogenetic embryonic stem (ES) cell lines have been derived. Although attempts to obtain full-term mouse and bovine parthenogenetic individuals have failed (3–5), chimeras of parthenogenetic cells with biparentally derived embryonic tissues have generated apparently normal offspring
AAAS