Increased mortality of ventilated patients with endotracheal Pseudomonas aeruginosa without clinical signs of infection

H Zhuo, K Yang, SV Lynch, RH Dotson… - Critical care …, 2008 - journals.lww.com
Objective: To investigate the frequency and outcomes of ventilated patients with newly
acquired large burdens of Pseudomonas aeruginosa and to test the hypothesis that large
quantities of bacteria are associated with adverse patient outcomes. Design: A prospective,
single-center, observational, cohort study. Setting: Medical-surgical intensive care units in a
tertiary care university hospital. Patients: All adult patients requiring≥ 48 hrs of mechanical
ventilation and identified as having newly acquired P. aeruginosa in their lower respiratory …