Deep brain stimulation for intractable obsessive compulsive disorder: pilot study using a blinded, staggered-onset design

WK Goodman, KD Foote, BD Greenberg, N Ricciuti… - Biological …, 2010 - Elsevier
BACKGROUND: Prior promising results have been reported with deep brain stimulation
(DBS) of the anterior limb of the internal capsule in cases with severe obsessive compulsive
disorder (OCD) who had exhausted conventional therapies. METHODS: In this pilot study,
six adult patients (2 male; 4 female) meeting stringent criteria for severe (minimum Yale-
Brown Obsessive Compulsive Scale [Y-BOCS] of 28) and treatment-refractory OCD had
DBS electrode arrays placed bilaterally in an area spanning the ventral anterior limb of the …