The clinical use of indocyanine green as a near‐infrared fluorescent contrast agent for image‐guided oncologic surgery
BE Schaafsma, JSD Mieog, M Hutteman… - Journal of surgical …, 2011 - Wiley Online Library
Journal of surgical oncology, 2011•Wiley Online Library
Optical imaging using near‐infrared (NIR) fluorescence provides new prospects for general
and oncologic surgery. ICG is currently utilised in NIR fluorescence cancer‐related surgery
for three indications: sentinel lymph node (SLN) mapping, intraoperative identification of
solid tumours, and angiography during reconstructive surgery. Therefore, understanding its
advantages and limitations is of significant importance. Although non‐targeted and non‐
conjugatable, ICG appears to be laying the foundation for more widespread use of NIR …
and oncologic surgery. ICG is currently utilised in NIR fluorescence cancer‐related surgery
for three indications: sentinel lymph node (SLN) mapping, intraoperative identification of
solid tumours, and angiography during reconstructive surgery. Therefore, understanding its
advantages and limitations is of significant importance. Although non‐targeted and non‐
conjugatable, ICG appears to be laying the foundation for more widespread use of NIR …
Abstract
Optical imaging using near‐infrared (NIR) fluorescence provides new prospects for general and oncologic surgery. ICG is currently utilised in NIR fluorescence cancer‐related surgery for three indications: sentinel lymph node (SLN) mapping, intraoperative identification of solid tumours, and angiography during reconstructive surgery. Therefore, understanding its advantages and limitations is of significant importance. Although non‐targeted and non‐conjugatable, ICG appears to be laying the foundation for more widespread use of NIR fluorescence‐guided surgery. J. Surg. Oncol. 2011; 104:323–332. © 2011 Wiley‐Liss, Inc.
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