Current management of lupus nephritis
FA Houssiau, BR Lauwerys - Best Practice & Research Clinical …, 2013 - Elsevier
Despite decades of clinical research aimed at finding the most appropriate
immunosuppressive regime, lupus nephritis (LN) remains one of the major disease
manifestations of systemic lupus erythematosus (SLE) with a great impact on survival and
quality of life. We start this review by defining the disease burden, the real-world challenges
and the poor prognostic factors. We then discuss the current anti-inflammatory, cytotoxic and
biologic therapies, with special emphasis on the need for optimal global care.
immunosuppressive regime, lupus nephritis (LN) remains one of the major disease
manifestations of systemic lupus erythematosus (SLE) with a great impact on survival and
quality of life. We start this review by defining the disease burden, the real-world challenges
and the poor prognostic factors. We then discuss the current anti-inflammatory, cytotoxic and
biologic therapies, with special emphasis on the need for optimal global care.