Cyclosporine (CsA), a widely used immunosuppressive drug, is an effective treatment of
sight-threatening posterior idiopathic uveitis. CsA's main side effect is nephrotoxicity. The
aim of this single-center prospective cohort study (conducted in a tertiary care teaching
hospital in Paris, France) was to assess the long-term renal tolerance of a low-dose CsA
treatment in patients with previously healthy kidneys on clinical, biologic, and pathologic
criteria. Forty-one patients treated with 4.3±1.6 mg/kg body wt per day CsA for 44.9±3.6 mo …