[HTML][HTML] Effect of platelet turnover on whole blood platelet aggregation in patients with coronary artery disease

EL Grove, AM Hvas, SB Mortensen, SB Larsen… - Journal of Thrombosis …, 2011 - Elsevier
Background: Previous studies have demonstrated considerable variation in the antiplatelet
effect of aspirin. Objectives: To investigate the impact of platelet turnover on the antiplatelet
effect of aspirin in patients with stable coronary artery disease (CAD) and to identify
determinants of platelet turnover. Methods: Platelet turnover was evaluated by
measurements of immature platelets and thrombopoietin in 177 stable CAD patients on
aspirin monotherapy, including 85 type 2 diabetics and 92 non‐diabetics. Whole blood …