[PDF][PDF] Pivotal role of calcium/calmodulin-dependent protein kinase II in ER stress-induced apoptosis

L Ozcan, I Tabas - Cell cycle, 2010 - Taylor & Francis
Pivotal role of calcium/calmodulin-dependent protein kinase II in ER stress-induced
apoptosis Page 1 www.landesbioscience.com Cell Cycle 223 Cell Cycle 9:2, 223-224;
January 15, 2010; © 2010 Landes Bioscience Features CeLL CyCLe Features Features
Conditions that interfere with proper functioning of the Endoplasmic Reticulum (ER), such
as the accumulation of misfolded proteins, lead to activation of the Unfolded Protein
Response (UPR). Initially, the UPR is protective, serving to restore ER homeostasis by …