Plasma biomarkers and kidney function decline in early and established diabetic kidney disease
Biomarkers of diverse pathophysiologic mechanisms may improve risk stratification for
incident or progressive diabetic kidney disease (DKD) in persons with type 2 diabetes. To
evaluate such biomarkers, we performed a nested case-control study (n= 190 cases of
incident DKD and 190 matched controls) and a prospective cohort study (n= 1156) using
banked baseline plasma samples from participants of randomized, controlled trials of early
(ACCORD) and advanced (VA NEPHRON-D) DKD. We assessed the association and …
incident or progressive diabetic kidney disease (DKD) in persons with type 2 diabetes. To
evaluate such biomarkers, we performed a nested case-control study (n= 190 cases of
incident DKD and 190 matched controls) and a prospective cohort study (n= 1156) using
banked baseline plasma samples from participants of randomized, controlled trials of early
(ACCORD) and advanced (VA NEPHRON-D) DKD. We assessed the association and …
