Association between CYP2C19 loss-of-function allele status and efficacy of clopidogrel for risk reduction among patients with minor stroke or transient ischemic attack
Y Wang, X Zhao, J Lin, H Li, SC Johnston, Y Lin, Y Pan… - Jama, 2016 - jamanetwork.com
Importance Data are limited regarding the association betweenCYP2C19genetic variants
and clinical outcomes of patients with minor stroke or transient ischemic attack treated with
clopidogrel. Objective To estimate the association betweenCYP2C19genetic variants and
clinical outcomes of clopidogrel-treated patients with minor stroke or transient ischemic
attack. Design, Setting, and Participants ThreeCYP2C19major alleles (* 2,* 3,* 17) were
genotyped among 2933 Chinese patients from 73 sites who were enrolled in the …
and clinical outcomes of patients with minor stroke or transient ischemic attack treated with
clopidogrel. Objective To estimate the association betweenCYP2C19genetic variants and
clinical outcomes of clopidogrel-treated patients with minor stroke or transient ischemic
attack. Design, Setting, and Participants ThreeCYP2C19major alleles (* 2,* 3,* 17) were
genotyped among 2933 Chinese patients from 73 sites who were enrolled in the …
