Loss of L‐selectin‐guided CD8+, but not CD4+, cells protects against ischemia reperfusion injury in a steatotic liver
VL Kolachala, S Palle, M Shen, A Feng… - Hepatology, 2017 - journals.lww.com
The acute hepatic porphyrias are a group of four inherited disorders, each resulting from a
deficiency in the activity of a specific enzyme in the heme biosynthetic pathway. These
disorders present clinically with acute neurovisceral symptoms which may be sporadic or
recurrent and, when severe, can be life‐threatening. The diagnosis is often missed or
delayed as the clinical features resemble other more common medical conditions. There are
four major subgroups: symptomatic patients with sporadic attacks (< 4 attacks/year) or …
deficiency in the activity of a specific enzyme in the heme biosynthetic pathway. These
disorders present clinically with acute neurovisceral symptoms which may be sporadic or
recurrent and, when severe, can be life‐threatening. The diagnosis is often missed or
delayed as the clinical features resemble other more common medical conditions. There are
four major subgroups: symptomatic patients with sporadic attacks (< 4 attacks/year) or …
