Characterization of mast cell activation syndrome

LB Afrin, S Self, J Menk, J Lazarchick - The American journal of the medical …, 2017 - Elsevier
Background Mast cell activation syndrome (MCAS), a recently recognized nonneoplastic
mast cell disease driving chronic multisystem inflammation and allergy, appears prevalent
and thus important. We report the first systematic characterization of a large MCAS
population. Method Demographics, comorbidities, symptoms, family histories, physical
examination and laboratory findings were reviewed in 298 retrospective and 115
prospective patients with MCAS. Blood samples from prospective subjects were examined …