Study of circadian melatonin secretion pattern at different stages of Parkinson's disease
R Bordet, D Devos, S Brique, Y Touitou… - Clinical …, 2003 - journals.lww.com
To explore changes in melatonin secretion patterns and biologic rhythms in Parkinson's
disease patients with or without levodopa-related motor complications (LDRMCs), the
authors investigated, in an observational study, circadian rhythms of central temperature,
motor activity, plasma cortisol, and melatonin in three groups: de novo untreated patients
(group I), patients treated with levodopa+ dopamine agonist and without LDRMCs (group II),
and patients treated with levodopa+ dopamine agonist and with LDRMCs (group III). There …
disease patients with or without levodopa-related motor complications (LDRMCs), the
authors investigated, in an observational study, circadian rhythms of central temperature,
motor activity, plasma cortisol, and melatonin in three groups: de novo untreated patients
(group I), patients treated with levodopa+ dopamine agonist and without LDRMCs (group II),
and patients treated with levodopa+ dopamine agonist and with LDRMCs (group III). There …
