Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: a double-blind, randomized, vehicle-controlled study
JK Geisse, P Rich, A Pandya, K Gross, K Andres… - Journal of the American …, 2002 - Elsevier
Background: Imiquimod 5% cream may provide an effective nonsurgical treatment for
superficial basal cell carcinoma (sBCC) based on results of previous studies. Objective: The
objective of this phase II dose-response study was to explore various dosing regimens using
imiquimod 5% cream for sBCC to find the most effective frequency of dosing with tolerable
side effects. Methods: Patients (n= 128) were dosed twice daily, once daily, 5 times a week,
or 3 times a week in this 12-week, randomized, double-blind, vehicle-controlled study. At 6 …
superficial basal cell carcinoma (sBCC) based on results of previous studies. Objective: The
objective of this phase II dose-response study was to explore various dosing regimens using
imiquimod 5% cream for sBCC to find the most effective frequency of dosing with tolerable
side effects. Methods: Patients (n= 128) were dosed twice daily, once daily, 5 times a week,
or 3 times a week in this 12-week, randomized, double-blind, vehicle-controlled study. At 6 …