Association between programmed death ligand 1 expression in patients with basal cell carcinomas and the number of treatment modalities

J Chang, GA Zhu, C Cheung, S Li, J Kim… - JAMA …, 2017 - jamanetwork.com
Importance Response to programmed death 1 (PD-1) inhibitors has been associated with
programmed death ligand 1 (PD-L1) expression levels in several cancers, but PD-L1
expression and its clinical significance in basal cell carcinoma (BCC) are unknown to date.
Objective To assess PD-L1 expression in treatment-naive and treated BCCs. Design,
Setting, and Participants This investigation was a cross-sectional study at a single academic
tertiary referral center. Immunohistochemical staining on formalin-fixed BCCs from a …