Arterial pressure monitoring in mice
X Zhao, D Ho, S Gao, C Hong… - Current protocols in …, 2011 - Wiley Online Library
X Zhao, D Ho, S Gao, C Hong, DE Vatner, SF Vatner
Current protocols in mouse biology, 2011•Wiley Online LibraryThe use of mice for the evaluation and study of cardiovascular pathophysiology is growing
rapidly, primarily due to the relative ease of developing genetically engineered mouse
models. Arterial pressure monitoring is central to the evaluation of the phenotypic changes
associated with cardiovascular pathology and interventions in these transgenic and
knockout models. There are four major techniques for measuring arterial pressure in the
mouse: tail‐cuff system, implanted fluid‐filled catheters, Millar catheters, and implanted …
rapidly, primarily due to the relative ease of developing genetically engineered mouse
models. Arterial pressure monitoring is central to the evaluation of the phenotypic changes
associated with cardiovascular pathology and interventions in these transgenic and
knockout models. There are four major techniques for measuring arterial pressure in the
mouse: tail‐cuff system, implanted fluid‐filled catheters, Millar catheters, and implanted …
Abstract
The use of mice for the evaluation and study of cardiovascular pathophysiology is growing rapidly, primarily due to the relative ease of developing genetically engineered mouse models. Arterial pressure monitoring is central to the evaluation of the phenotypic changes associated with cardiovascular pathology and interventions in these transgenic and knockout models. There are four major techniques for measuring arterial pressure in the mouse: tail‐cuff system, implanted fluid‐filled catheters, Millar catheters, and implanted telemetry systems. Here we provide protocols for their use and discuss the advantages and limitations of each of these techniques. Curr. Protoc. Mouse Biol. 1:105‐122. © 2011 by John Wiley & Sons, Inc.
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