Neonatal brain abnormalities and memory and learning outcomes at 7 years in children born very preterm
C Omizzolo, SE Scratch, R Stargatt, H Kidokoro… - Memory, 2014 - Taylor & Francis
Memory, 2014•Taylor & Francis
Using prospective longitudinal data from 198 very preterm and 70 full term children, this
study characterised the memory and learning abilities of very preterm children at 7 years of
age in both verbal and visual domains. The relationship between the extent of brain
abnormalities on neonatal magnetic resonance imaging (MRI) and memory and learning
outcomes at 7 years of age in very preterm children was also investigated. Neonatal MRI
scans were qualitatively assessed for global, white-matter, cortical grey-matter, deep grey …
study characterised the memory and learning abilities of very preterm children at 7 years of
age in both verbal and visual domains. The relationship between the extent of brain
abnormalities on neonatal magnetic resonance imaging (MRI) and memory and learning
outcomes at 7 years of age in very preterm children was also investigated. Neonatal MRI
scans were qualitatively assessed for global, white-matter, cortical grey-matter, deep grey …
Using prospective longitudinal data from 198 very preterm and 70 full term children, this study characterised the memory and learning abilities of very preterm children at 7 years of age in both verbal and visual domains. The relationship between the extent of brain abnormalities on neonatal magnetic resonance imaging (MRI) and memory and learning outcomes at 7 years of age in very preterm children was also investigated. Neonatal MRI scans were qualitatively assessed for global, white-matter, cortical grey-matter, deep grey-matter, and cerebellar abnormalities. Very preterm children performed less well on measures of immediate memory, working memory, long-term memory, and learning compared with term-born controls. Neonatal brain abnormalities, and in particular deep grey-matter abnormality, were associated with poorer memory and learning performance at 7 years in very preterm children. Findings support the importance of cerebral neonatal pathology for predicting later memory and learning function.
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