Cilia are microtubule-based structures that protrude from the cell surface and function as
sensors for mechanical and chemical environmental cues that regulate cellular
differentiation or division. In metazoans, ciliary signaling is important during organismal
development and in the homeostasis controls of adult tissues, with receptors for the
Hedgehog, platelet derived growth factor (PDGF), Wnt, and other signaling cascades
arrayed and active along the ciliary membrane. In normal cells, cilia are dynamically …