Kidney surveillance in the spotlight: contrast-induced acute kidney injury illuminated
Simon J. Atkinson
Simon J. Atkinson
Published July 2, 2018; First published June 4, 2018
Citation Information: J Clin Invest. 2018;128(7):2754-2756. https://doi.org/10.1172/JCI121741.
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Category: Commentary

Kidney surveillance in the spotlight: contrast-induced acute kidney injury illuminated

Abstract

Acute kidney injury comprises a heterogeneous group of conditions characterized by a sudden decrease in renal function over hours to days. Contrast-induced acute kidney injury (CI-AKI) is caused by radiographic contrast agents used in diagnostic imaging. In the current issue of the JCI, Lau et al. use a mouse model of CI-AKI to study the role of resident and infiltrating phagocytes, recruited leukocytes, and tubular cells in the immune surveillance response to contrast agents. This study has the potential to provide innovative therapies for human CI-AKI.

Authors

Simon J. Atkinson

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