Emerging infectious diseases

Series edited by Andrew R. Marks

This series examines six different pathogens in order to illustrate the selective forces that drive the emergence of new infectious diseases and the implications for public health and our survival.

Published March 2004

Cellular senescence

Series edited by Pier Giuseppe Pelicci

Cellular life span is restrained by signaling pathways activated by DNA damage, telomere dysfunction, and environmental stresses. Cells entering a state of senescence undergo a permanent cell cycle arrest, and functional and morphological changes. This series investigates the molecular pathways associated with execution of the senescence program and how it contributes to aging and tumor suppression.

Published January 2004

Quorum sensing

Series edited by E. Peter Greenberg

Researchers have only recently realized that bacteria use cell-to-cell communication in order to orchestrate gene expression during infection - a phenomenon known as quorum sensing. This series explores the role of these signaling mechanisms and bacterial group behavior in evading host defenses and antibiotics.

Published November 2003

Genetic repair

Series edited by Bruce Sullenger

This series examines the inspired techniques utilized in targeted gene repair for the simple correction of genetic defects and the hurdles that must be overcome in order to make clinical use of molecular therapeutics in the treatment of diseases such as cystic fibrosis, hemophilia, sickle cell anemia, muscular dystrophy, and ß-thalassemia.

Published August 2003

Medical imaging

Series edited by Joy Hirsch

Advances in medical imaging have allowed for further understanding of human diseases. This series covers new developments in imaging from novel techniques to the ethics of whole body scans.

Published May 2003

Redox signaling in biology and disease

Series edited by Roy Soberman

This series discusses various mechanisms by which oxygen and reducing equivalents create cellular damage and how they have been adapted to transmit information within cells.

Published March 2003

Neurodegeneration

Series edited by Serge Przedborski

Articles in this series review selected genetic and molecular advances relevant to the biology of neurodegeneration. Readers obtain a comprehensive update on prominent neurodegenerative conditions from both a clinical and a molecular viewpoint.

Published January 2003

Cellular responses to aggregated proteins associated with human disease

Series edited by David H. Perlmutter

This series discusses our current understanding of protein folding and the mechanisms by which disease-associated proteins aggregate, injure cells, and trigger responses designed to protect cells from such injury.

Published November 2002

Biology and biochemistry of cholesterol

Series edited by Ira A. Tabas

An essential component of healthy cells, cholesterol in excess is a major culprit of atherosclerosis. This series covers a number of interesting topics related to the physiological and pathophysiological roles of this fascinating molecule.

Published September 2002

The future of vaccine design

Series edited by Adolfo Garcia-Sastre and Peter Palese

Articles in this series discuss ways to increase vaccine efficiency in general, and review advances and challenges in developing and improving vaccines for bacterial and viral diseases as well as cancer.

Published June 2002